A Game-Changer: 86% Fewer HIV Infections in Two PrEP Studies

Two studies of PrEP in gay men and trans women have demonstrated that the availability of PrEP reduced the rate of infection by 86%. This amounts to the highest effectiveness yet seen for PrEP and is superior to most other HIV prevention interventions. Extraordinarily, two separate studies which provided PrEP in very different ways found exactly the same level of effectiveness. The PROUD study was conducted in England and the IPERGAY study in France and Canada. Both recruited men who have sex with men and trans women who were at elevated risk of acquiring HIV – they had multiple partners, condom use was inconsistent or irregular, rates of sexually transmitted infections (STIs) were high, many participants had needed post-exposure prophylaxis (PEP) before and recreational drug use was common.

Dr Michael Brady, medical director at Terrence Higgins Trust, commented: "PrEP is, quite simply, a game-changer. We know that most gay men use condoms most of the time, and that this has prevented tens of thousands of HIV infections since the epidemic began in the UK. However, we also know that condomless sex vastly increases the risk of HIV being transmitted. This research shows just how effective PrEP can be in preventing transmission of the virus in groups at greatest risk; offering another line of defence alongside condoms and regular testing. It is not a vaccine and it won’t be for everyone, but once approved, we expect it to significantly increase the momentum in our fight against the virus. Therefore, we urge the Government, NHS England and Local Authorities to make PrEP a key priority in the fight against HIV."

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Credited Source: 
NAM Aidsmap

Culture Stats & Facts

  • Black African MSM appear twice as likely to contract HIV as other ethnic groups

    (Sigma Research, 2011)

  • BAME MSM make up 0.1% of the total population in the UK, but 13% of MSM diagnosed with HIV.

    (Nastal-3, PHE, 2013)

  • Black MSM are also twice as likely to report homophobic attacks in their local area compared to the white population - 13% compared to 6% respectively

    (Stonewall, 2013)